Factors Associated with Hypertension-related Strokes at a Community Hospital in Southern Thailand

Abstract

Stroke rates are increasing significantly worldwide. Comorbidity disease especially hypertension that an important modifiable risk factor for increasing the incidence of stroke and worsening outcomes. Furthermore, the burden of hypertension as a comorbidity of stroke in rural areas was limited, Therefore, the aim of this study was focus to evaluate factors associated with stroke patients having hypertension at Ratsada Hospital, Trang Province, southern Thailand. Materials and methods: A retrospective study was conducted by utilizing data from the January 1, 2018, to December 31, 2022 hospital database. Diagnoses of patients are identified by using ICD-10 (I60-I69), totaling, 333 patient records. The cumulative incidence rates of stroke with or without hypertension were calculated by using Logistic regression models to evaluate risk factors. Results: A total of 191 stroke patients with hypertension (57.36%); median [25th-75th percentile] age 72 [61-80] years) and 142 stroke patients without hypertension (42.64%); median [25th-75th percentile] age 61 [52-71] years. Factors associated with increased risk of stroke were age 60 years and above (AOR=2.66; CI:1.59-4.44; p<0.001), and high diastolic blood pressure (≥85 mmHg) (AOR=2.05; CI:1.19-3.53; p=0.010). In addition, glomerular filtration rate values of 60-89 ml/min/1.73 m2 (AOR=1.95; CI:1.14-3.34; p=0.014) and 30-59 ml/min /1.73 m2 (AOR=1.99; CI:1.02-3.89; p=0.043) were significant. Conclusion: This study found that age 60 and above, high diastolic blood pressure and specific glomerular filtration rate ranges were the potential risk factors of stroke with hypertension as a comorbidity disease. This finding suggests that providing intensive care for controlling and managing risk factors, especially in older adults.