Metastatic Follicular Variant of Papillary Thyroid Carcinoma Arising From Struma Ovarii: A Case Report
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Abstract
The follicular variant of papillary thyroid carcinoma arising from struma ovarii rarely occurs, usually asymptomatic with a risk of distant metastasis. We present a case of a 37-year-old female diagnosed with malignant struma ovarii, which has histopathologic characteristics of a follicular variant of papillary thyroid carcinoma. She was discovered to have a left ovarian cyst during her second pregnancy, and laparoscopic cystectomy was performed for the left multiloculated follicular cyst. The histopathological examination came back as struma ovarii. During a subsequent pregnancy, she underwent open left salpingo-oophorectomy for a twisted left ovarian cyst. The histopathology of her left ovary revealed a follicular type of papillary thyroid carcinoma arising from struma ovarii. Following that, total thyroidectomy was performed and histopathology revealed papillary thyroid microcarcinoma. Computed tomography (CT) scan staging showed bilateral lung metastases. Subsequently, she underwent radioactive iodine therapy and survived without recurrence after six years of follow-up.
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