Institutional Diagnostic Reference Level for CT Thorax in a University Hospital

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Nurul Dizyana Nor Azman
Rabiatul Adawiyah Mohamad Jan
Rafidah Supar
Nurul Saadiah Shamsuddin

Abstract

Introduction: Pandemic of COVID-19 in 2020 has seen the rise of computed tomography (CT) thorax as the gold standard modality. CT exposes patients to the highest radiation; hence, routinely assessing dose optimisation is essential. This study conducted to establish a diagnostic reference level (DRL) for CT thorax in an institution and assess conformity to the established national standard. In this study, the values weighted CT dose index (CTDIw), CT Dose index volume (CTDIv) and dose length product (DLP) were collected and correlated to the patient’s age, body mass index (BMI) and values were compared between genders. DRL in CTDIw and DLP were presented as 75th percentile as suggested by ICRP. Materials and methods: Patient data and dose related to CT thorax (N = 83) were collected retrospectively through system from December 2022 until May 2023. Results: The institution dose presented 12.93 mGy for CTDIvol, 7.63 mGy for CTDIw and 553 mGy.cm for DLP. DLP value in this study slightly higher by 21% and CTDIw were significantly lower by 64% compared with MOH Malaysia. There is significant correlation between CTDIw and DLP with BMI which suggesting that the higher the patient’s BMI, the higher the CTDIw value. Subsequently, there is no significant different between genders (P > 0.05). Conclusion: The DRL value suggested for this institution are within the national and international level. The requisite for further dose optimisation for CT thorax according to the patient’s demographics to reduce the feasible stochastic effects and application of ALARA concepts to the patients.

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Nor Azman, N. D., Mohamad Jan, R. A., Supar, R., & Shamsuddin, N. S. (2025). Institutional Diagnostic Reference Level for CT Thorax in a University Hospital. Malaysian Journal of Medicine and Health Sciences, 21(5), 70–77. https://doi.org/10.47836/mjmhs.21.5.9
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Original Articles

References

Abdulkadir MK, Piersson AD, Musa GM, Audu SA, Abubakar A, Muftaudeen B, et al. Assessment of diagnostic reference levels awareness and knowledge amongst CT radiographers. Egypt J Radiol Nucl Med. 2021;52(1). doi:10.1186/s43055-021-00444-x.

Hashim JH, Adman MA, Hashim Z, Mohd Radi MF, Kwan SC. COVID-19 epidemic in Malaysia: Epidemic progression, challenges, and response. Front Public Health. 2021;9:560592. doi:10.3389/fpubh.2021.560592.

Shah V, Keniya R, Shridharani A, Punjabi M, Shah J, Mehendale N. Diagnosis of COVID-19 using CT scan images and deep learning techniques. Emerg Radiol. 2021;28(3):497–505. doi:10.1007/s10140-020-01886-y.

Trinh CD, Le VN, Le VNB, Pham NT, Le VD. Lung abnormalities on computed tomography of Vietnamese patients with COVID-19 and the association with medical variables. IJID Reg. 2024;10:183–90. doi:10.1016/j.ijidregi.2024.01.006.

Li K, Liu X, Yip R, Yankelevitz DF, Henschke CI, Geng Y, et al. Early prediction of severity in coronavirus disease (COVID-19) using quantitative CT imaging. Clin Imaging. 2021;78:223–9. doi:10.1016/j.clinimag.2021.02.004.

Abuzaid MM, Elshami W, Sulieman A, Bradley D. Cumulative radiation exposure, effective and organ dose estimation from multiple head CT scans in stroke patients. Radiat Phys Chem. 2022;199:110306. doi:10.1016/j.radphyschem.2022.110306.

International Commission on Radiological Protection. Radiological protection and safety in medicine. ICRP Publication 73. Ann ICRP. 1996;26(2).

International Commission on Radiological Protection. Diagnostic Reference Level in Medical Imaging. ICRP Publication 135. Ann ICRP. 2017;46(1):1–144. doi:10.1177/0146645317717209.

Paulo G, Damilakis J, Tsapaki V, Schegerer AA, Repussard J, Jaschke W, et al. Diagnostic Reference Levels based on clinical indications in computed tomography: a literature review. Insights Imaging. 2020;11(1):96. doi:10.1186/s13244-020-00899-y.

The Measurement, Reporting and Management of Radiation Dose in CT. AAPM Report No. 96. American Association of Physicists in Medicine. Available from: [https://www.aapm.org/pubs/reports/rpt_96.pdf](https://www.aapm.org/pubs/reports/rpt_96.pdf).

McCollough C, Branham T, Herlihy V, Bhargavan M, Robbins L, Bush K, et al. Diagnostic reference levels from the ACR CT Accreditation Program. J Am Coll Radiol. 2011;8(11):795–803. doi:10.1016/j.jacr.2011.03.014.

The Measurement, Reporting and Management of Radiation Dose in CT. AAPM Report No. 96. American Association of Physicists in Medicine. Available from: [https://www.aapm.org/pubs/reports/rpt_96.pdf](https://www.aapm.org/pubs/reports/rpt_96.pdf).

Järvinen H, Vassileva J, Samei E, Wallace A, Vano E, Rehani M. Patient dose monitoring and the use of diagnostic reference levels for the optimization of protection in medical imaging: current status and challenges worldwide. J Med Imaging (Bellingham). 2017;4(3):031214. doi:10.1117/1.JMI.4.3.031214.

Mayo-Smith WW, Hara AK, Mahesh M, Sahani DV, Pavlicek W. How I do it: Managing radiation dose in CT. Radiology. 2014;273(3):657–72. doi:10.1148/radiol.14132328.

Gan YS, Akmal S, Hamzaini AH, Khadijah MN, Mazli MZ, Muhammad KAK. Radiation Dose Comparison in CT Thorax, CT Abdomen and CT Thorax-Abdomen-Pelvis (TAP) Using 640-and 160-Slice Computed Tomography (CT) Scanners. J Sains Kesihatan Malaysia. 2020;18(1):29–36. doi:10.17576/JSKM-2020-1801-05.

Brat H, Zanca F, Montandon S, Racine D, Rizk B, Meicher E, et al. Local clinical diagnostic reference levels for chest and abdomen CT examinations in adults as a function of body mass index and clinical indication: a prospective multicenter study. Eur Radiol. 2019;29(12):6794–804. doi:10.1007/s00330-019-06257-x.

Kayun Z, Abdul Karim MK, Harun HH, Shaari AH, Mahmud R, Hamid HA, et al. Radiation doses and size-specific dose estimate from CT brain examinations according to head sizes in a tertiary hospital in Malaysia. Radiat Phys Chem. 2021;189:109694. doi:10.1016/j.radphyschem.2021.109694.

Vañó E, Miller DL, Martin CJ, Rehani MM, Kang K, Rosenstein M, et al. ICRP publication 135: Diagnostic reference levels in medical imaging. Ann ICRP. 2017;46(1):1–144. doi:10.1177/0146645317717209.

Perchik JD, Murphy RP, Kelly DM, Sawyer JR. Radiation exposure in adult and pediatric patients with osteogenesis imperfecta. J Orthop. 2019;16(4):320–4. doi:10.1016/j.jor.2019.03.008.

Kharita MH, Al-Naemi H, Arru C, Omar AJ, Aly A, Tsalafoutas I, et al. Relation between age and CT radiation doses: Dose trends in 705 pediatric head CT. Eur J Radiol. 2020;130:109138. doi:10.1016/j.ejrad.2020.109138.

Deevband MR, Mohammadi H, Salimi Y, Mostaar A, Deravi N. Body-Mass Index-Based Effective Dose Determination in Commonly Performed Computed Tomography Examinations in Adults. Front Biomed Technol. 2022;9(4). doi:10.18502/fbt.v9i4.10425.

Mohammadbeigi A, Khoshgard K, Haghparast A, Eivazi MT. Local DRLs for paediatric CT examinations based on size-specific dose estimates in Kermanshah, Iran. Radiat Prot Dosimetry. 2019;186(4):496–506. doi:10.1093/rpd/ncz056.

Yang Y, Zhuo W, Zhao Y, Xie T, Wang C, Liu H. Estimating specific patient organ dose for chest CT examinations with Monte Carlo method. Appl Sci. 2021;11(19):8961. doi:10.3390/app11198961.

Palma G, Sorice GP, Genchi VA, Giordano F, Caccioppoli C, D’Oria R, et al. Adipose tissue inflammation and pulmonary dysfunction in obesity. Int J Mol Sci. 2022;23(13):7349. doi:10.3390/ijms23137349.

McLaughlin PD, Chawke L, Twomey M, Murphy KP, O’Neill SB, McWilliams SR, et al. Body composition determinants of radiation dose during abdominopelvic CT. Insights Imaging. 2018;9(1):9–16. doi:10.1007/s13244-017-0577-y.

Narendran N, Luzhna L, Kovalchuk O. Sex Difference of Radiation Response in Occupational and Accidental Exposure. Front Genet. 2019;10:260. doi:10.3389/fgene.2019.00260.

Boos J, Thomas C, Appel E, Klosterkemper Y, Schleich C, Aissa J, et al. Institutional computed tomography diagnostic reference levels based on water-equivalent diameter and size-specific dose estimates. Phys Med Biol. 2018;63(2):025012. doi:10.1088/1361-6498/aaa32c.

Indrayan A, Mishra A. The importance of small samples in medical research. J Postgrad Med. 2021;67(4):219–23. doi:10.4103/jpgm.JPGM_230_21.