Multiple Bone Fracture in Neonates With Suspected Osteogenesis Imperfecta: A Case Report and Review of the Management

Abstract

Osteogenesis imperfecta (OI) is a rare hereditary skeletal dysplasia characterized by bone fragility, deformity, and short stature. In this case report, we provide an overview of the management of a suspected OI case in a peripheral hospital. A suspected case of OI in a 1-month-old neonate boy presents with typical clinical conditions including reduced mobility, bowed legs, shortened limbs, blue sclera, and pectus excavatum chest. The radiological finding showed a spiral fracture in the right and left femur. This patient was initially diagnosed type 1 OI with differential diagnoses of rickets and idiopathic juvenile osteoporosis. The initial management for this patient is to reduce the fracture angulation with skin traction, and then bilateral spica cast was performed after the appropriate angulation angle. Multidisciplinary management is recommended for these cases, including pediatric, orthopedic, and rehabilitation management.