Anti-cancer Activity of Strobilanthes crispus Against Colon Cancer Cell Lines: A Scoping Review of Literature
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Abstract
Being the third most common cancer case in men and the second in women, colon cancer affecting approximately 1.36 million people worldwide. Strobilanthes crispus, herb native to Madagascar, Malaysia, and Indonesia, has been studied for its medicinal properties, including anticancer effects. This study aims to review the anti-proliferative activity of S. crispus against colon cancer cell lines through systematic review of data and literature. From a number of 515 articles gathered from the search, 221 were passed for final analysis. The results indicate that S. crispus effectively induces colon cancer cells death over time while sparing healthy cells. While existing studies suggest the herb’s anticancer potential, the findings are not yet conclusive and further clinical research is recommended to explore its effectiveness in treating colon cancer patients.
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