Rapid Orbital and Optic Nerve Infiltration In a Lady With Aggressive Diffuse Large B-cell Lymphomaa

Sharon Yet Xue Er; Sujaya Singh; Nandini Vijaya Singham; Sangeeta Kuganasan

doi:10.47836/mjmhs.v22i2.1593

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Published: Mar 15, 2026

DOI: https://doi.org/10.47836/mjmhs.v22i2.1593

Keywords:

Orbital lymphoma, Optic nerve infiltration, DLBCL

Sharon Yet Xue Er

UM Eye Research Centre (UMERC), Department of Ophthalmology, Faculty of Medicine, Universiti Malaya, 50603 Wilayah Persekutuan Kuala Lumpur, Malaysia.

Sujaya Singh

UM Eye Research Centre (UMERC), Department of Ophthalmology, Faculty of Medicine, Universiti Malaya, 50603 Wilayah Persekutuan Kuala Lumpur, Malaysia

Nandini Vijaya Singham

Department of Ophthalmology, Tuanku Ja’afar Seremban Hospital, Bukit Rasah, 70300 Seremban, Malaysia

Sangeeta Kuganasan

Department of Ophthalmology, Tuanku Ja’afar Seremban Hospital, Bukit Rasah, 70300 Seremban, Malaysia

Abstract

Diffuse Large B-cell lymphoma (DLBCL) with optic nerve lymphomatous infiltration is generally uncommon. Undeniably, its resemblance in clinical manifestations across various optic nerve conditions makes its diagnosis difficult. This article presents a case of rapid neoplastic invasion of optic nerve, orbit in a DLBCL patient, which raised diagnosis challenges of ocular toxoplasmosis with Jensen papillitis

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How to Cite

Er, S. Y. X., Singh, S., Singham, N. V., & Kuganasan, S. (2026). Rapid Orbital and Optic Nerve Infiltration In a Lady With Aggressive Diffuse Large B-cell Lymphomaa. Malaysian Journal of Medicine and Health Sciences, 22(2), 1593 . https://doi.org/10.47836/mjmhs.v22i2.1593

Issue

Vol. 22 No. 2 (2026)

Section

Case Report

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