Anti-N-methyl-D-aspartate receptor (NMDAR) Encephalitis in Malaysia: A Review Article

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Published: Jan 31, 2021
Keywords:
Anti-NMDAR encephalitis, NMDAR antibody, Autoimmune, Encephalitis, Malaysia

Main Article Content

Su Tein Sim
A.H Lee Specialist Clinic, 38-1, Jalan 52/4, Bandar Baru Petaling Jaya, 46200 Petaling Jaya, Selangor, Malaysia
Peck Kee Chia
Department of Neurology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
Keng Hong Chhoa
Department of Psychiatry, Hospital Kuala Lumpur, Jalan Pahang, 50586 Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur
Bin Shen Chai
Department of Obstetric & Gynaecology, Hospital Sungai Buloh, Jalan Hospital, 47000 Sungai Buloh, Selangor, Malaysia

Abstract

N-methyl-D-aspartate receptor (NMDAR) antibody encephalitis is recognized as an autoimmune encephalitis, which is due to autoantibodies against synaptic NMDAR. This disorder affects individuals aged 23 months to 76 years and has a wide range of presentations. In Malaysia, more than 20 cases have been reported. Timely diagnosis and de- finitive immunotherapy are vital in optimizing functional recovery and prognosis. However, early diagnosis of the condition is often missed due to low awareness among clinicians in Malaysia. This article gathered the medical liter- ature from Malaysia and highlights the aetio-pathophysiology, clinical presentation and management of the disease.

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How to Cite
Sim, S. T., Chia, P. K., Chhoa, K. H., & Chai, B. S. (2021). Anti-N-methyl-D-aspartate receptor (NMDAR) Encephalitis in Malaysia: A Review Article. Malaysian Journal of Medicine and Health Sciences, 17(1), 163–169. Retrieved from http://mjmhsojs.upm.edu.my/index.php/mjmhs/article/view/187
Issue
Vol. 17 No. 1 (2021)
Section
Review Article

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