Mycoplasma pneumoniae - The Culprit for Juvenile Dermatomyositis in A 9-Year-Old Girl: A Case Report
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Abstract
Mycoplasma pneumoniae is frequently known as an “atypical bacterium” that can cause wide-ranging extrapul- monary manifestations. Here, we outline a case of a child, aged 9-year-old, who presented with profound proximal muscle weaknesses and a vague rash, associated with markedly elevated serum creatinine kinase (CK). Muscle biopsy suggested Juvenile Dermatomyositis (JDM) following an upper respiratory illness of M. pneumoniae origin. The child responded exceptionally well to a combined therapy of immunoglobulin, intravenous glucocorticoid and methotrexate.
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Wargula JC. Update on juvenile dermatomyositis: new advances in understanding its etiopathogenesis. Current Opinion in Rheumatology. 2003;15 (5):595-601
Gara S, Jamil RT, Muse ME, Noureddine L. Juvenile Dermatomyositis. [Updated 2020 Jul 2]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-.
Patwardhan A, Rennebohm R, Dvorchik I, Spencer CH. Is juvenile dermatomyositis a different disease in children up to three years of age at onset than in children above three years at onset? A retrospective review of 23 years of a single center’s experience. Pediatric Rheumatology. 2012; 10:34
Manlhiot C, Liang L, Tran D, Bitnun A, Tyrrell PN, Feldman BM. Assessment of an infectious disease history preceding juvenile dermatomyositis symptom onset. Rheumatology. 2008;47:526-529.
Narita M. Classification of extrapulmonary manifestations due to Mycoplasma pneumoniae infection on the basis of possible pathogenesis. Front Microbiol. 2016 Jan 28; 7:23