Immature Brain Teratoma of An Infant In A University Hospital: A Case Report
Main Article Content
Abstract
Teratomatous tumours of the head are rather uncommon. We report a 3-month-old child who presented with acute signs of raised intracranial pressure, needing craniectomy and subtotal tumour removal. The patient was diagnosed as intracranial immature teratoma grade 3, from the pathological study and elevated alpha-fetoprotein (AFP). Managing brain teratoma posed a challenge to the managing team due to the location of the tumour, the unavailability of standardized chemotherapy protocol and the dilemma of commencing adjuvant chemotherapy in a very young infant. The tumour was partially removed due to its critical location. And chemotherapy was delayed until the patient achieved 7 months of age. After four rounds of chemotherapy, the patient remained in remission for more than three years follow up.
Downloads
Article Details
References
Chakravarti A, Shashidhar TB, Naglot S, Sahni
JK. Head and neck teratomas in children: a case
series. Indian J Otolaryngol Head Neck Surg.
;63(2):193-197. doi:10.1007/s12070-011-02
-8
Damjanov I, Andrews PW. Teratomas produced
from human pluripotent stem cells xenografted
into immunodeficient mice - a histopathology
atlas. Int J Dev Biol. 2016;60(10-11-12):337-419.
doi:10.1387/ijdb.160274id.
Sugimoto M, Kurishima C, Masutani S, Tamura
M, Senzaki H. Congenital Brain Tumor within
the First 2 Months of Life. Pediatr Neonatol.
Dec;56(6):369-75. doi: 10.1016/j.ped neo.
04.004.
Yin-Hsiu C, Po-Nien T, Wang-Tso L, Shinn-Feng
P, Kuo-Inn TY. Congenital intracranial teratoma.
Pediatric Neurology 2000; 22(1): 72-4. doi:
1016/s0887-8994(99)00103-4.
Maghrabi Y, Kurdi ME, Baeesa SS. Infratentorial
immature teratoma of congenital origin can be
associated with a 20-year survival outcome: a case
report and review of literature. World J Surg Oncol.
;17(1):22. doi:10.1186/s12957-019-1564-1.