Cryptococcal Meningitis Disguised As A Stroke: A Case Report

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Fatimahtuz Zahrah Muhamad Damanhuri
Siti Zulaikha Zakariah
Fatimatulzahra Abdul GhanI

Abstract




We present a case of cryptococcal meningitis initially misdiagnosed as stroke. Our patient is a young man on long- term corticosteroid due to gouty arthritis, who presented with acute onset of left-sided body weakness. Computed tomography of the brain revealed multifocal chronic lacunar infarcts with acute communicating hydrocephalus and cerebrospinal fluid culture isolated Cryptococcus neoformans. He was subsequently treated with amphotericin B and fluconazole but passed away due to multiorgan failure. This case report highlights the importance of considering chronic meningitis as a differential diagnosis when encountering stroke in young and immunocompromised patients.




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How to Cite
Muhamad Damanhuri, F. Z., Zakariah, S. Z., & Abdul GhanI, F. (2022). Cryptococcal Meningitis Disguised As A Stroke: A Case Report. Malaysian Journal of Medicine and Health Sciences, 18(5), 225–227. https://doi.org/10.47836/mjmhs18.5.32
Section
Case Report

References

Qu J, Zhou T, Zhong C, Deng R, Lü X. Comparison of clinical features and prognostic factors in HIV- negative adults with cryptococcal meningitis and tuberculous meningitis: a retrospective study. BMC

Infect Dis. 2017 Jan 10;17(1):51–51. doi: 10.1186/ s12879-016-2126-6.

Hao Lai C, Yu Lin G, Tay Lee J, Wen Kao H, Han Ho T, Kai Lin Y, et al. A Rare Case of Cryptococcus Meningoencephalitis Presenting with Acute Brainstem Infarction in an Immunocompetent Host. Neuropsychiatry [Internet]. 2017 [cited 2020 Dec

;07(06). doi:10.4172/Neuropsychiatry.1000285

Tarhan B, Mehkri Y, De Prey J, Hu C, Tuna IS, Shuhaiber H. Cryptococcosis Presenting as Cerebrovascular Disease. Cureus [Internet]. 2021 Nov 10 [cited 2022 Jan 21]; doi:10.7759/ cureus.19442

Vela-Duarte D, Nyberg E, Sillau S, Pate A, Castellanos P, Chastain DB, et al. Lacunar Stroke in Cryptococcal Meningitis: Clinical and Radiographic Features. J Stroke Cerebrovasc Dis. 2019 Jun;28(6):1767–72. doi:10.1016/j.

jstrokecerebrovasdis.2018.12.043

Tan Z-R, Long X-Y, Li G-L, Zhou J-X, Long L. Spectrum of neuroimaging findings in cryptococcal meningitis in immunocompetent patients in China — A series of 18 cases. J Neurol Sci. 2016 Sep;368:132–7. doi:10.1016/j.jns.2016.06.069