Acute Mycoplasma Pneumoniae Encephalitis in an Adult

Abstract

Mycoplasma pneumonia is an atypical bacterium that causes mild respiratory tract infections, especially in the upper respiratorysystem. Mycoplasma pneumoniae infection is infrequently associated with various CNS manifestations such as encephalitis, meningoencephalitis, myelitis, Guillain-Barre syndrome and acute disseminated encephalomy- elitis (ADEM). Here we report a rarecase of mycoplasma encephalitis in an adult who presented with a first episode of seizure following fever and neck stiffness for oneweek. Mycoplasma pneumoniae antibody titer was markedly elevated at >1:320 and MRI brain revealed encephalitic changes witha lesion in the splenium. Interestingly, there was no associated respiratory infection and his stay in the hospital was also complicatedby SIADH. The patient im- proved after treatment with a macrolide antibiotic.