Orally Disintegrating Film: A Review of Its Formulation and Manufacturing Method

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Published: Nov 30, 2023
DOI: https://doi.org/10.47836/mjmhs.19.6.39
Keywords:
Orally disintegrating film, Solvent casting, Hot melt extrusion, Compliance, Polymer

Main Article Content

Kai Bin Liew
Faculty of Pharmacy, University of Cyberjaya, Persiaran Bestari, 63000 Cyberjaya, Selangor, Malaysia
Ganesan Gobal
Faculty of Pharmacy, University of Cyberjaya, Persiaran Bestari, 63000 Cyberjaya, Selangor, Malaysia
Hanifah Mohd Rofiq
Faculty of Pharmacy, University of Cyberjaya, Persiaran Bestari, 63000 Cyberjaya, Selangor, Malaysia
Hiu Ching Phang
Faculty of Pharmacy, University of Cyberjaya, Persiaran Bestari, 63000 Cyberjaya, Selangor, Malaysia
Siew-Keah Lee
M. Kandiah Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Jalan Sungai Long, Bandar Sungai Long, 43000, Kajang, Selangor, Malaysia
Long Chiau Ming
School of Medical and Life Sciences, Sunway University, Sunway City, 47500 Malaysia
A.B.M. Helal Uddin
Faculty of Pharmacy, International Islamic University Malaysia, Bandar Indera Mahkota, Kuantan, Pahang, Malaysia
Yik Ling Chew
Faculty of Pharmaceutical Sciences, UCSI University, Jalan Menara Gading, UCSI Heights, 56000 Cheras, Kuala Lumpur, Malaysia
Vijayakumar Lakshminarayanan
Department of Pharmaceutical Technology, Hindusthan Institute of Technology, Coimbatore, Tamilnadu - 641032, India

Abstract

Oral route drug delivery system is still considered as the most convenient and patient friendly drug delivery route. Over the decades, many research has been performed to improve the functionality oral dosage form. Orally disin- tegrating film (ODF) is a newer oral drug delivery system, which is in the form of a thin film that will disintegrate in the oral cavity within a matter of seconds. The aim of this review paper is to recap ODF, its benefits, formulation contents and manufacturing method. With more research and development work has been conducted on ODF, the dosage form is expected to be manufactured and scaled up to be commercializable products to be sold in the market.

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How to Cite
Bin Liew, K., Gobal, G., Mohd Rofiq, H., Ching Phang, H., Lee, S.-K., Chiau Ming, L., Helal Uddin, A., Ling Chew, Y., & Lakshminarayanan, V. (2023). Orally Disintegrating Film: A Review of Its Formulation and Manufacturing Method. Malaysian Journal of Medicine and Health Sciences, 19(6), 297–303. https://doi.org/10.47836/mjmhs.19.6.39
Issue
Vol. 19 No. 6 (2023)
Section
Review Article
Crossref
Scopus
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Europe PMC

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