Prevalence of Transfusion-transmissible Infections in Blood Donors: A Private Hospital Experience
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Abstract
Introduction: Blood transfusion, a vital component of established medical protocols, has the potential to save lives and enhance well-being. Nonetheless, it carries inherent risks, with transfusion-transmissible infections (TTIs) re- maining a global public health concern. Vigilant monitoring of TTI prevalence among blood donors and understand- ing of evolving patterns are crucial safety endeavours. The objective of this study was to assess the prevalence of TTIs and their patterns among blood donors within a private hospital’s transfusion service. Methods: This retrospective study involved TTI testing results of blood donations at Normah Medical Specialist Centre (NMSC) in Kuching, Sar- awak, spanning a decade from 2010 to 2019. Results: A total of 7329 blood donors contributed 16,085 blood units (2010 – 2019). Among them, 353 donors exhibited reactivity to TTIs, resulting in a prevalence of 4.81%. The major- ity of reactive donors were male (87.3%), of Malay ethnicity (62.6%), and first-time donors (73.9%). The prevalence rates were highest for HCV (2.69%), followed by HBV (1.41%), HIV (0.42%), and syphilis (0.39%). Both HBV and HCV demonstrated declining prevalence trends, while the prevalence of HIV and syphilis remained consistently low. The response to notification of positivity among reactive donors stood at a mere 4.0%, and the seroconversion rate among repeat donors reached 36.9%. No significant disparities in prevalence or response rates were observed between first-time and repeat donors. Conclusions: The prevalence of TTIs within NMSC’s blood donor populace remains relatively low, though not negligible. The responsiveness of reactive donors to notifications displayed con- siderable deficiencies.
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